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1

Total Synthesis of Discodermolide: Optimization of the Effective Synthetic Route

Elsa de Lemos, François-Hugues Porée, Arnaud Bourin, Julien Barbion, Evangelos Agouridas, Marie-Isabelle Lannou, Alain Commerçon, Jean-François Betzer, Ange Pancrazi, Janick Ardisson

Journal:

Chemistry - A European Journal

Year:

2008

Language:

english

File:

PDF, 555 KB

english, 2008

2

α-Oxygenated Crotyltitanium and Dyotropic Rearrangement in the Total Synthesis of Discodermolide

Elsa de Lemos, François-Hugues Porée, Alain Commerçon, Jean-François Betzer, Ange Pancrazi, Janick Ardisson

Journal:

Angewandte Chemie

Year:

2007

Language:

english

File:

PDF, 147 KB

english, 2007

3

α-Oxygenated Crotyltitanium and Dyotropic Rearrangement in the Total Synthesis of Discodermolide

Elsa de Lemos, François-Hugues Porée, Alain Commerçon, Jean-François Betzer, Ange Pancrazi, Janick Ardisson

Journal:

Angewandte Chemie International Edition

Year:

2007

Language:

english

File:

PDF, 147 KB

english, 2007

4

Conception, Synthesis, and Biological Evaluation of Original Discodermolide Analogues

Dr. Elsa de Lemos, Dr. Evangelos Agouridas, Dr. Geoffroy Sorin, Dr. Antonio Guerreiro, Dr. Alain Commerçon, Dr. Ange Pancrazi, Dr. Jean-François Betzer, Dr. Marie-Isabelle Lannou, Prof. Janick Ardisso

Journal:

Chemistry - A European Journal

Year:

2011

Language:

english

File:

PDF, 457 KB

english, 2011

5

ChemInform Abstract: A Convenient Method for the Preparation of 3-Azetidinylidene Acetic Acid

Marc Vuilhorgne, Alain Commercon, Serge Mignani

Journal:

Year:

1999

File:

PDF, 26 KB

1999

6

ChemInform Abstract: Preparation of Lavendamycin Analogues.

Christine Barbier, Arnaud Joissains, Alain Commercon, Jean-Francois Riou, Francois Huet

Journal:

Year:

2000

File:

PDF, 26 KB

2000

7

1,3-Dipolar Cycloaddition Route to Novel Isoxazole-Type Derivatives Related to Combretastatin A-4.

Julia Kaffy, Claude Monneret, Patrick Mailliet, Alain Commercon, Renee Pontikis

Journal:

Year:

2004

File:

PDF, 149 KB

2004

8

2-Monosubstituted-1,3-oxazolidines as improved protective groups of N-boc-phenylisoserine in docetaxel preparation

Eric Didier, Elie Fouque, Isabelle Taillepied, Alain Commerçon

Journal:

Tetrahedron Letters

Year:

1994

Language:

english

File:

PDF, 407 KB

english, 1994

9

Preparation of 7-modified docetaxel analogs using electrochemistry

Jean-Pierre Pulicani, Hervé Bouchard, Jean-Dominique Bourzat, Alain Commerçon

Journal:

Tetrahedron Letters

Year:

1994

Language:

english

File:

PDF, 344 KB

english, 1994

10

Direct access to 2-debenzoyl taxoids by electrochemistry, synthesis of 2-modified docetaxel analogs

Jean-Pierre Pulicani, Daniel Bézard, Jean-Dominique Bourzat, Hervé Bouchard, Martine Zucco, Dominique Deprez, Alain Commerçon

Journal:

Tetrahedron Letters

Year:

1994

Language:

english

File:

PDF, 352 KB

english, 1994

11

Improved access to 19-nor-7β, 8β-methylene-taxoids and formation of a 7-membered C-ring analog of doxetaxel by electrochemistry

Hervé Bouchard, Jean-Pierre Pulicani, Marc Vuilhorgne, Jean-Dominique Bourzat, Alain Commerçon

Journal:

Tetrahedron Letters

Year:

1994

Language:

english

File:

PDF, 333 KB

english, 1994

12

Semisynthesis of RPR 121056A, a major metabolite of irinotecan (CPT-11)

Jean-Dominique Bourzat, Marc Vuilhorgne, Laurent P. Rivory, Jacques Robert, Alain Commerçon

Journal:

Tetrahedron Letters

Year:

1996

Language:

english

File:

PDF, 183 KB

english, 1996

13

Constrained analogs of KCVFM with improved inhibitory properties against farnesyl transferase

François-Frédéric Clerc, Jean-Dominique Guitton, Nadine Fromage, Yves Lelièvre, Marc Duchesne, Bruno Tocqué, Evelyne James-Surcouf, Alain Commerçon, Jérôme Becquart

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1995

Language:

english

File:

PDF, 373 KB

english, 1995

14

Onium salt supported peptide synthesis

Céline Roche, Mathieu Pucheault, Michel Vaultier, Alain Commerçon

Journal:

Year:

2010

Language:

english

File:

PDF, 761 KB

english, 2010

15

1,3-Dipolar cycloaddition route to novel isoxazole-type derivatives related to combretastatin A-4

Julia Kaffy, Claude Monneret, Patrick Mailliet, Alain Commerçon, Renée Pontikis

Journal:

Tetrahedron Letters

Year:

2004

Language:

english

File:

PDF, 261 KB

english, 2004

16

Partial synthesis of major human metabolites of docetaxel

Alain Commerçon, Jean-Dominique Bourzat, Daniel Bézard, Marc Vuilhorgne

Journal:

Year:

1994

Language:

english

File:

PDF, 778 KB

english, 1994

17

Stereoselective synthesis of racemic α-amino-acid derivatives with a β-lactam skeleton: Application of the Staudinger reaction to chiral imines of methyl glyoxylate

Michel Barreau, Alain Commerçon, Serge Mignani, Dominique Mouysset, Patricia Perfetti, Lucien Stella

Journal:

Year:

1998

Language:

english

File:

PDF, 1.32 MB

english, 1998

18

A practical access to chiral phenylisoserinates, preparation of Taxotere® analogs

Jean Dominique Bourzat, Alain Commerçon

Journal:

Tetrahedron Letters

Year:

1993

Language:

english

File:

PDF, 269 KB

english, 1993

19

Electrochemical reduction of taxoids: Selective preparation of 9-dihydro-, 10-deoxy- and 10-deacetoxy-taxoids

Jean-Pierre Pulicani, Jean-Dominique Bourzat, Hervé Bouchard, Alain Commerçon

Journal:

Tetrahedron Letters

Year:

1994

Language:

english

File:

PDF, 465 KB

english, 1994

20

Expeditious semisynthesis of docetaxel using 2-trichloromethyl-1,3-oxazolidine as side-chain protection

Eric Didier, Elie Fouque, Alain Commerçon

Journal:

Tetrahedron Letters

Year:

1994

Language:

english

File:

PDF, 165 KB

english, 1994

21

Synthesis of 19-hydroxy docetaxel from a novel baccatin

Rodolphe Margraff, Daniel Bézard, Jean Dominique Bourzat, Alain Commerçon

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1994

Language:

english

File:

PDF, 284 KB

english, 1994

22

Synthesis and biological activity of Para-substituted 3′-phenyl docetaxel analogs

Jean-Dominique Bourzat, François Lavelle, Alain Commerçon

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1995

Language:

english

File:

PDF, 304 KB

english, 1995

23

Selective inhibition of tyrosine protein kinase by a synthetic multisubstrate analog

Isabelle Baginski, Alain Commerçon, Bruno Tocqué, Geneviève Colson, Aurelio Zerial

Journal:

Biochemical and Biophysical Research Communications

Year:

1989

Language:

english

File:

PDF, 583 KB

english, 1989

24

Structure-Activity Relationships in a Series of 5-[(2,5-Dihydroxybenzyl)amino]salicylate Inhibitors of EGF-Receptor-Associated Tyrosine Kinase: Importance of Additional Hydrophobic Aromatic Interactions

Chen, Huixiong, Boiziau, Janine, Parker, Fabienne, Mailliet, Patrick, Commercon, Alain, Tocque, Bruno, Le Pecq, Jean-Bernard, Roques, Bernard-Pierre, Garbay, Christiane

Journal:

Journal of Medicinal Chemistry

Year:

1994

Language:

english

File:

PDF, 2.08 MB

english, 1994

25

Electrochemical Attachment of Organic Groups to Carbon Felt Surfaces

Coulon, Estelle, Pinson, Jean, Bourzat, Jean-Dominique, Commerçon, Alain, Pulicani, Jean Pierre

Journal:

Year:

2001

Language:

english

File:

PDF, 149 KB

english, 2001

26

Surface-Modified Carbon Felts: Possible Supports for Combinatorial Chemistry

Coulon, Estelle, Pinson, Jean, Bourzat, Jean-Dominique, Commerçon, Alain, Pulicani, Jean-Pierre

Journal:

Journal of Organic Chemistry

Year:

2002

Language:

english

File:

PDF, 117 KB

english, 2002

27

Novel Conformationally Extended Naphthalene-Based Inhibitors of Farnesyltransferase

Burns, Christopher J., Guitton, Jean-Dominique, Baudoin, Bernard, Lelièvre, Yves, Duchesne, Marc, Parker, Fabienne, Fromage, Nadine, Commerçon, Alain

Journal:

Journal of Medicinal Chemistry

Year:

1997

Language:

english

File:

PDF, 178 KB

english, 1997

28

Predominant Labeling of .beta.- over .alpha.-Tubulin from Porcine Brain by a Photoactivatable Taxoid Derivative

Combeau, Cecile, Commercon, Alain, Mioskowski, Charles, Rousseau, Bernard, Aubert, Francois, Goeldner, Maurice

Journal:

Year:

1994

Language:

english

File:

PDF, 1.33 MB

english, 1994

29

Chameleon catches in combinatorial chemistry: Tebbe olefination of polymer supported esters and the synthesis of amines, cyclohexanones, enones, methyl ketones and thiazoles

Ball, Christopher P., Barrett, Anthony G. M., Compère, Delphine, Kuhn, Cyrille, Roberts, Richard S., Smith, Marie L., Venier, Olivier, Commerçon, Alain

Journal:

Chemical Communications

Year:

1998

Language:

english

File:

PDF, 75 KB

english, 1998

30

Synthesis of 2′-deoxy-2′-spirocyclopropyl cytidine as potential inhibitor of ribonucleotide diphosphate reductase

Czernecki, Stanislas, Mulard, Laurence, Valéry, Jean-Marc, Commerçon, Alain

Journal:

Canadian Journal of Chemistry

Year:

1993

Language:

english

File:

PDF, 294 KB

english, 1993

31

A Convenient Method for the Preparation of 3-Azetidinylidene Acetic Acid

Vuilhorgne, Marc, Commerçon, Alain, Mignani, Serge

Journal:

Chemistry Letters

Year:

1999

File:

PDF, 286 KB

1999

32

ChemInform Abstract: ALKOXY- UND ALKYLTHIOVINYL-KUPFERVERBINDUNGEN, ZWISCHENPRODUKTE BEI DER SYNTHESE STERESPEZIFISCH IN ENTGEGENGESETZTEM SINNE SUBSTITUIERTER ALKENE

NORMANT, JEAN-FRANCOIS, ALEXAKIS, ALEXANDRE, COMMERCON, ALAIN, CAHIEZ, GERARD, VILLIERAS, JEAN

Journal:

Chemischer Informationsdienst

Year:

1975

File:

PDF, 206 KB

1975

33

ChemInform Abstract: DURCH KUPFERSALZE KATALYSIERTE ALKYLIERUNG VON JODALKENEN MIT ORGANO-MG- UND ORGANO-LI-VERBINDUNGEN

NORMANT, JEAN-F., COMMERCON, ALAIN, CAHIEZ, GERARD, VILLIERAS, JEAN

Journal:

Chemischer Informationsdienst

Year:

1974

File:

PDF, 134 KB

1974